Allergist - Twittering on
#allergy
,
#asthma
&
#immunology
. Associate Professor of Immunology , del Salvador University, WAO website social media editor
The
#FDA
has approved
#tezepelumab
- ekko for self-administration in a prefilled, single-use pen among patients aged 12 years and older with severe
#asthma
.
The US Food and Drug Administration (FDA) has approved benralizumab (Fasenra) for the treatment of adults with eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome.
“Grandfather of allergy, Dr William Frankland, aged 106, on inventing the pollen count, working with Alexander Fleming and spending 70 years in the NHS”
Covid-19: New allergic reactions to hair dye reported. Hairdressers in parts of the UK are reporting clients having new allergic reactions, like rashes and burns, to hair dye after contracting coronavirus.
Dupilumab could become the first approved biologic for COPD, as it has shown positive results in two phase III trials. This treatment not only reduces exacerbations but also improves lung function.
#COPD
#Dupilumab
LENZILUMAB EFFICACY AND SAFETY IN NEWLY HOSPITALIZED COVID-19 SUBJECTS: RESULTS FROM THE LIVE-AIR PHASE 3 RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL
“Anti-immunoglobulin E (IgE) and anti-interleukin-5 (IL-5) therapies showed similar efficacy in controlling
#asthma
symptoms, but none were associated with significant improvements in lung function.”
Allergic Rhinitis: What Do We Know About Allergen-Specific Immunotherapy? This review presents an updated overview of Allergen-Specific Immunotherapy with a special focus on Allergic Rhinitis.
Top story:
@annasalacunill
: 'The last day of
@EAACI_JM
@EAACI_HQ
congress
#EAACI2021
talking about the “Planetary health in 2021”!! Thanks Dra.Annesi-Maesano for emphasixing the importance of avoiding plastic and to sh… , see more
Predicting the course of
#asthma
from childhood until early adulthood: lung function, allergic comorbidity and polysensitization in childhood predict the course of asthma. Open Access
Tezspire (tezepelumab) approved in the US for severe
#asthma
,
First and only biologic to consistently and significantly reduce exacerbations in a broad population of severe asthma patients with no phenotype or biomarker limitations
Revised guidelines for diagnosing and treating allergic bronchopulmonary aspergillosis/mycoses have been released by the ISHAM-ABPA working group. Stay updated with the latest recommendations!
#ISHAM
#ABPA
.
FDA has approved the first oral device for treating severe sleep apnea, offering an alternative to CPAP and surgical neurostimulation implants.
#SleepApneaTreatment
#FDAApproval
“A PHARMACIST IS being praised for saving a teenager who went into anaphylactic shock on Dublin’s O’Connell Street after eating a peanut brownie by accident”
The FDA has given high priority to omalizumab for the treatment of food allergies. This is great news for those who suffer from this condition.
#FoodAllergyTreatment
#FDAApproval
#Anticentromere
antibodies (ACAs) can serve as a diagnostic serologic marker for
#Sj
ögren syndrome, and patients with ACA-positivity should be examined for Sjögren syndrome.
A better understanding of how treatment changes affect asthma inflammatory phenotypes and airway neutrophils may help guide
#asthma
treatment strategies.
#Prenatal
#Factors
in the Development of
#Allergic
#Diseases
. This study aims to highlight the mechanisms that induce allergic reactions, how they progress, and which prenatal factors influence their development.
$FDA approved the spray from drugmaker ARS Pharmaceuticals Inc. as an emergency treatment for adults and older children experiencing life-threatening allergic reactions known as
#anaphylaxis
. The first needle-free alternative to shots like EpiPen.
Top story:
@Aller_MD
: '“Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID-19”… , see more
The nasal microbiome in
#asthma
: Nasal microbiome composition differs in subjects with exacerbated asthma, nonexacerbated asthma, and healthy controls.
Since
#IL
-5-neutralizing monoclonal antibodies are currently available for clinical use, this review revisit the role of IL-5 in
#asthma
pathogenesis and airway remodelling, in addition to exploring its role as a target for
#biological
treatments.
Oral Antiviral Stops SARS-CoV-2 in its Tracks: A single pill of the investigational drug molnupiravir taken twice a day for 5 days eliminated SARS-CoV-2 from the nasopharynx of 49 participants.
Subcutaneous immunotherapy (SCIT) may be a valuable adjunct for specific individuals with eosinophilic esophagitis (EoE) who have comorbid allergic rhinitis, according to researchers from the U. of North Carolina (UNC) School of Medicine.
#AAAAI2024
A new study from Washington University School of Medicine in St. Louis supports evidence that children with mild asthma can effectively manage the condition by using their two inhalers—one a steroid and the other a bronchodilator—when symptoms occur.
#Basophils
in
#pruritic
skin
#diseases
. Since basophils and neurons share many receptors and channels, bidirectional interaction mechanisms, which drive the sensation of itch, are highlighted in this
#review
. Open Access.
New research shows that combining dupilumab with antihistamines is more effective than using antihistamines alone for treating chronic spontaneous urticaria (CSU). Find out more about this breakthrough treatment here:
#CSU
#treatment
Allergy: Vol 79, No 9. This issue is dedicated to Marcus
#Maurer
in recognition of his groundbreaking contributions to the fields of
#dermatology
and
#allergy
.
“FDA has approved Opzelura (ruxolitinib) cream for the short-term and noncontinuous chronic treatment of mild to moderate atopic dermatitis in nonimmunocompromised patients 12 years of age and older whose disease is not adequately controlled.”
Researchers at the University of Alabama at Birmingham have shown -; for the first time -; that established lung fibrosis can be reversed using metformin.
The EAACI “Global Atlas of
#Asthma
” 2021 has just published today.
It has been written by an international group of 216 opinion leaders in asthma and includes 109 chapters, 202 illustrations and 93 tables. Read the Global Atlas here:
“Treatment with antihistamines oxatamide, fexofenadine, and ebastine were associated with significant hair regrowth in patients with alopecia areata (AA)”
Eggs, legumes including soya and peanuts, almonds and cashew nuts are now being introduced earlier in infant diets following revised advice on the introduction of certain foods. There has been no change in the rate of
#food
#allergies
or eczema in infants.
Top story:
@ShellyGray100
: 'Common theme today is the detrimental effect of highly processed foods on the gut barrier and inflammation
#eaaciasn22
' , see more
"Maximizing the Effectiveness of In Vitro Tests for Drug Allergy Diagnosis: Clinical Insights . A clinical viewpoint enhances the potential of in vitro tests in identifying drug allergies.
#DrugAllergy
#ClinicalInsights
"
Top story:
@pai_eaaci
: 'Editor's choice.
Pathogenesis, immunology, and immune-targeted management of the multisystem inflammatory syndrome in children or pediatric inflammatory multisystem syndrome: EAACI Position Pape… , see more
Oral immunotherapy, a potential solution for food allergies in young children, is currently supported by evidence and underlying mechanisms. Discover more about this curative treatment.
#foodallergies
#immunotherapy
#Asthma
and
#COPD
are different diseases with differing underlying inflammatory patterns, but some patients have a mixed picture, as these common diseases may coexist. Peter Barnes...
#Nasal
powder formulations of
#epinephrine
are effective and show superior stability to EpiPens, according to a study presented at the annual meeting of the
#AAAAI24
NSAID-exacerbated respiratory disease: Older age, family history of asthma or allergic rhinitis, cumulative exposure to tobacco smoke, secondhand smoke, and occupational exposures increased odds of N-ERD. N-ERD was associated with significant morbidity.
The Use of
#Azelastine
/
#Fluticasone
in the Management of
#Allergic
#Rhinitis
in Asia: A Review; published data on the efficacy and safety of its prolonged use in adults and children have validated that effective treatment of AR.
The airway neuro-immune axis is a promising target for treating allergic airway diseases. Check out this link for more information: .
#allergies
#airwaydiseases
Top story:
@ProfGRoberts
: '
#EAACI2021
: Honoured to be awarded a Fellowship of the European Academy of Allergy & Clinical Immunology with Prof M Akdis, Bousquet & Durham. Everything I have done has only been possible wit… , see more
Recent findings suggest that
#dupilumab
, a monoclonal antibody treatment for atopic dermatitis (AD), may significantly reduce the risk of
#atopic
#march
in children.
Mount Sinai researchers have identified a genetic biomarker of
#asthma
that can be tested for using a simple nasal brush and basic follow-up data analysis.
A phase 2 clinical study of universal influenza vaccine begins in USA: The vaccine contains antigenic peptide sequences shared among many different influenza viruses.
“Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence”