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Andy Webb Profile
Andy Webb

@AJWPharm

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Neurocritical Care Clinical Pharmacist @MGHNeuroICU | BCCCP | Alum @OHSUPharmRes , @MayoPharmRes , @URI_Pharmacy | #rstats | He/him |

Boston, MA
Joined April 2019
Don't wanna be here? Send us removal request.
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@AJWPharm
Andy Webb
2 years
I've made a number of infographics since joining Twitter and many are buried in my timeline I figured I'd start a thread of all the infographics I've made over the years so they are more readily available! 👇 🖼️
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@AJWPharm
Andy Webb
5 years
Can we start a drug name story thread? I'll start Ambien got its name from a little bit of crappy Spanish - after your night's sleep, you should have an AM that is bien
@CartoonsSide
CounterSideCartoons
5 years
VICODIN'S NAME comes from the fact that it is 6 times stronger than codeine so, they used VI (the roman numeral for 6) + CODeINe (dropped the e's from codeine)= VICODIN
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@AJWPharm
Andy Webb
4 years
What law of physics dictates that your badge will always flip to its back side no matter how many times you flip it the right way
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@AJWPharm
Andy Webb
1 year
Attention📢📢 : New aneurysmal subarachnoid hemorrhage guidelines just dropped! Lots of new updates to the last guidelines published in 2012, lets check them out below 👇
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@AJWPharm
Andy Webb
4 years
The ECMO circuit causes a number of changes to how medications distribute throughout the body - here's a quick guide to some of the most common clinically relevant considerations!
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@AJWPharm
Andy Webb
3 years
Big life announcement! After a trial of westward expansion, I'm coming home - I am elated to announce I accepted a position as a neurosciences clinical pharmacist at Mass Gen! I can't wait to move to Boston and start the job I've been dreaming of since pharmacy school 🧠
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Andy Webb
5 years
Did you see @NEJM recently released new guidelines for the use of P values in clinical trials? I thought I'd put together a little guide to understand how they are misused/misinterpreted for PGY1s (or anyone who wants a refresher!)
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@AJWPharm
Andy Webb
3 years
How to summon a pharmacist
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@AJWPharm
Andy Webb
3 years
Sci-Hub added a button to collapse the giant left panel in the PDF reader A perfect tool got even more perfect
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@AJWPharm
Andy Webb
2 years
The unspoken perk of fabric posters is their second life as a blanket
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@AJWPharm
Andy Webb
2 years
Imposter syndrome is often billed as a feeling that you made it into your position because of a mistake, but my special brand of evolved imposter syndrome™ is not that I feel like I'm unqualified; it's that I feel like I am constantly underperforming despite my qualifications
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@AJWPharm
Andy Webb
2 years
We've had a few patients with mitochondrial diseases recently and I've had to refresh myself on the details of the ol powerhouses of the cell. While each disease is unique, there is a common set of meds to avoid. I put together a 1-pager for common ones! #NeuroCritCare
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@AJWPharm
Andy Webb
3 years
Day 3 of toxicology rotation and I am officially afraid to eat food
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@AJWPharm
Andy Webb
4 years
My team after I tell them not to order ceftriaxone on a susceptible Kleb aerogenes for the 9th time
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@AJWPharm
Andy Webb
2 years
Just a reminder that anticoagulants do not thin your blood and a stroke is not an accident
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@AJWPharm
Andy Webb
3 years
Trying to remember even the names all of the available antiepileptic drugs can be challenging, let alone their place in therapy. One way I like to think about them is by their "spectrum of activity," just like how we think about antibiotics! 🧠 #NeuroPharm
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@AJWPharm
Andy Webb
4 years
Remind me again why the hell pharmacists are the only healthcare professional (that I know of) that needs to take a separate licensing exam for state laws? If I read one more shall, may, should, or must my head is going to explode
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@AJWPharm
Andy Webb
5 years
Warfarin is a classic, a coumARIN discovered at the Wisconsin Agricultural Research Foundation (WARF) after investigating why so many cows were hemorrhaging after eating moldy sweet clover
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@AJWPharm
Andy Webb
1 year
As a resident, I loved the rabbit holes I was sent down trying answer to a question. I post many of them here, but I can't capture nuance in 280 characters Introducing Neu℞oWise - a place to share some deep dives and thoughts on pharmacotherapy in NCC!
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@AJWPharm
Andy Webb
2 years
Oh my GOD 🙌🙌🙌🙌
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@AJWPharm
Andy Webb
7 months
New CSVT Scientific Statement - LMWH officially preferred over heparin and official endorsement of DOACs!
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@AJWPharm
Andy Webb
2 years
This tweet serves as a reminder that sometimes, they really do just need the vanc to be q18
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@AJWPharm
Andy Webb
3 years
When the patient is on nimodipine, nicardipine, and amlodipine
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@AJWPharm
Andy Webb
4 years
Do you ever get over the feeling of overwhelming guilt when you're not constantly doing something productive asking for a friend
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@AJWPharm
Andy Webb
5 years
I am SO excited to announce my first publication finally hit press today! Learned a lot through this process (including...patience) and I'm thrilled to share our workflow for pharmacists to evaluate renal clearance/IBW in transgender patients.
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@AJWPharm
Andy Webb
3 years
Officially have more letters after my name than before Andrew Webb, PharmD, BCCCP Thanks to all the preceptors and mentors who got me here!
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@AJWPharm
Andy Webb
4 years
Guess I should join the party - this season I had to decide between two specialties I loved and knew I would grow so much in: crit care and ID. I ultimately landed right where I wanted. I'm so excited to announce I will be continuing on for a PGY2 in critical care @OHSUNews !
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@AJWPharm
Andy Webb
1 month
When you write "expect vanc trough to be 15 after dose adjustment" in your note and it comes back at 15.0
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@AJWPharm
Andy Webb
4 years
Does anyone else get oddly uncomfortable when you see the bottom half of someone's face for the first time after having met them wearing a mask or just me
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@AJWPharm
Andy Webb
7 months
*arrives at patient room out of breath* I heard there were intestinal cholesterol uptake transporters that were uninhibited and I got here as fast as I could!
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@AJWPharm
Andy Webb
8 months
Free VPA levels are unpredictable in the ICU, but an equation was just validated to estimate free VPA levels in ICU patients - the Fraser equation @CBthePHARMD To make it more user-friendly, I made an app and am hosting it on Neurxowise, check it out!
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@AJWPharm
Andy Webb
1 year
A key point in ACLS is that in shockable rhythms, the ⚡ is key to improving outcomes A knee-jerk reaction in a code is to give epi, but epi before shock in a shockable rhythm WORSENS outcomes ⚡once, then ⚡ again, THEN give epi
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@AJWPharm
Andy Webb
2 years
Another day, another patient on an oral onc drug I've never heard of
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@AJWPharm
Andy Webb
3 years
Ok maybe orgo is useless for everyday practice but how else would my team have appreciated my rounds-stopping med chem fun facts like how Onfi (clobazam) got its name because it's a ONe-FIve nitrogen substituted benzo rather than a 1,4 giving it higher GABA α-2 subunit affinity
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@AJWPharm
Andy Webb
1 year
@amyfaithho For someone who says they value pharmacists you really love dunking on pharmacists huh
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@AJWPharm
Andy Webb
4 years
Continuing my ampC adventures in the MICU Me: Hafnia is ampC Team: well it's not that virulent so continue Zosyn Hafina then now
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@AJWPharm
Andy Webb
4 years
I have an entire CE to put together this weekend so naturally my apartment is immaculate
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@AJWPharm
Andy Webb
4 years
Walked out of Mayo for the last time today; what a surreal experience While this year was... Unorthodox, I still experienced immense personal and professional growth and had a ton of fun doing it. I can't thank my preceptors and mentors enough for their guidance! On to PGY2!
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@AJWPharm
Andy Webb
2 years
@MeganARech @JACCPJournal @gmjones09 @beaverspharmd "working with difficult physician colleagues did not influence rate of burnout; however, working with difficult pharmacist colleagues increased the odds of burnout by 110%." We are truly our own worst enemy... Awesome, much needed article! Great work!
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@AJWPharm
Andy Webb
1 year
European Stroke Organization released an expedited recommendation for TNK: expert consensus recommends tenecteplase OVER alteplase given potential safety benefits and ease of administration! Highlights from committee meta analysis below 👇
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@AJWPharm
Andy Webb
1 year
Please no, we are all so tired
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@AJWPharm
Andy Webb
1 year
Fun pharmacy catch today - Patient had rapidly rising phos but normal Cr and normal Ca and had not received any phos repletion during stay (and RN confirmed lab drawn off A line) The culprit? The A-line had heparinized saline running which is buffered with sodium phos
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@AJWPharm
Andy Webb
2 years
Dropping everything for this
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@AJWPharm
Andy Webb
2 years
While not typically considered to contribute to seizures, high-dose chronic levodopa can lead to refractory pyridoxine deficiency seizures Levodopa needs B6 as a cofactor in its metabolism to dopamine, leading to depletion, ⬇️GABA production, and seizure
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@AJWPharm
Andy Webb
2 years
Always inspired by the grit and perseverance of providers who soldier through every duplicate order warning when they put in an entire 20-order order set twice
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@AJWPharm
Andy Webb
2 years
Every look at a vasopressor receptor affinity table and think... but why? Some minor structural differences between agents can greatly change how pressors interact with α and β receptors. (This doesn't work with dobutamine whose pesky (+) and (-) enantiomers act differently)
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@AJWPharm
Andy Webb
3 years
"They fevered through oral tylenol"
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@AJWPharm
Andy Webb
1 year
Putting through the 5th vanc/cefepime of the morning
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@AJWPharm
Andy Webb
2 years
The ANNEXA-4 statistician running the 37th post-hoc adjusted model of the trial data in a desperate attempt to squeeze every p<0.05 out of the trial data set
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@AJWPharm
Andy Webb
2 years
I'm giving a talk on manuscript writing for our residents in a few weeks - the last section is "quality of life" tips for making writing easier. Some are obvious (citation software, etc), but what are some QoL things you have discovered that improve your writing experience?
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@AJWPharm
Andy Webb
4 years
Finds interesting fact in review article Citation is another review article Review article cites textbook Textbook cites another textbook Older textbook has no citation
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@AJWPharm
Andy Webb
3 years
When the trough for the vanc you dosed isn't exactly in range
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@AJWPharm
Andy Webb
4 years
There's nothing quite like the feeling when a seasoned MICU attending is gearing up to teach the team something on rounds but then turns to you and says "correct me if I'm wrong"
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@AJWPharm
Andy Webb
4 years
Honored to have won this award and can't wait to continue my research career!
@CCPharmacists
Critical Care Pharmacists
4 years
Congratulations to these @SCCM CPP section award/scholarship winners!👏👏👏 ⭐️Distinguished Service Award - Joe Dasta ⭐️Congress Scholarship - @SESmithPharmD ⭐️Innovations in Patient and Medication Safety - Alexa Nardone ⭐️Young Pharmacist Investigator - @AJWPharm #PharmICU
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@AJWPharm
Andy Webb
4 years
VFib in the field: ⚡, 5 epis, amio AND lido. More ⚡⚡& epi in resus with no luck Esmolol 500mcg/kg bolus then infusion and they sail to ROSC and the cath lab Probably the mix of it all but this will forever be my "one time we used esmolol" story Ok ED is kinda cool
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@AJWPharm
Andy Webb
11 months
My favorite story of this myth in action was when vanc/cefepime was ordered for UTI - I called asking why they needed vanc & the response was to cover enterococcus When I suggested pip/tazo monotherapy, they pushed back, d/t concern for nephrotoxicity But they were ok with vanc
@PulmCrit
𝙟𝙤𝙨𝙝 𝙛𝙖𝙧𝙠𝙖𝙨 💊
11 months
PIPERACILLIN-TAZOBACTAM IS NOT NEPHROTOXIC: exploring the arc of a myth over time this was clearly a myth in 2016: blog from 2022 exploring the evolution of this myth: fresh RCT to finally settle this:
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@AJWPharm
Andy Webb
28 days
We know IV push Keppra is safe, but status-sized loading doses remain unexplored vs piggyback I'm excited to share former PGY2 EM @MadisonKoons1 's work on IVP LEV loads (vs IVPB): - Faster time to admin - No incr in ADEs - Potential ⬇️ICU admits in SE!
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@AJWPharm
Andy Webb
2 years
Ahh precepting, a fulfilling experience of helping to develop the next generation of pharmacists made only sweeter by the requirement to fill out a 20 page, 47 item evaluation
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@AJWPharm
Andy Webb
2 years
The man himself #SCCM2023
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Andy Webb
3 years
Attending: "I think this patient needs some albumin" *Looks at me* "Sorry"
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@AJWPharm
Andy Webb
3 years
I finish residency in 19 days, and I just got an email that my password expires in 20 days
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Andy Webb
3 years
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@AJWPharm
Andy Webb
3 years
My Epic training just forced me to order clindamycin for pneumonia and I have never cringed so hard clicking sign and verify
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@AJWPharm
Andy Webb
2 years
If your patient with ESRD is bradycardic, please don't forget to check if atenolol is on their home med list They may have been in the hospital for a few days, but their last dose of atenolol is still along for the ride Oh, and if you see it - discontinue it
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@AJWPharm
Andy Webb
4 years
#OTILT is the saying "piss like a race horse" refers to horses being given a dose of furosemide prior to a race to reduce the risk of exercise induced pulmonary hemorrhage and improve race performance I'm not sure what to do with this information but there you go
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@AJWPharm
Andy Webb
5 months
Patience pays off - at long last, our final manuscript on bromocriptine for central fever has been published! We describe 30 pts where bromocriptine was used for central fever. It was modestly effective overall, although some patients (esp SAH patients) saw a dramatic response
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@AJWPharm
Andy Webb
3 years
Thrilled to see my PGY1 research in print today! TEG fans will be excited to see we found K time and a angle were significantly associated with hemorrhage expansion in patients with severe TBI Thanks to my team and mentors @Dre_pharmd @CBthePHARMD for helping this come to life!
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@AJWPharm
Andy Webb
3 years
I'm thinking we could use a "10 false beliefs of critical care pharmacotherapy" I'll start: resuming vanc in a decompensating patient without evidence of MRSA will not change the patient's outcome
@edgarvlermamd
Edgar V. Lerma 🇵🇭
3 years
The 10 False Beliefs in Adult Critical Care Nephrology #KidneyWk #Nephpearls
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@AJWPharm
Andy Webb
1 year
Time is brain shown once again 🧠 Delayed initiation of therapy in first time status epilepticus is associated with increased likelihood of recurrent unprovoked seizures in a large prospective registry Give that (full dose) benzo asap!
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@AJWPharm
Andy Webb
2 years
TRACE-2: Yet another win for TNK - if you haven't switched yet, why not?
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@AJWPharm
Andy Webb
4 years
This sentence is a first for me: "He was started on meropenem and nitrofurantoin."
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@AJWPharm
Andy Webb
2 years
Guidelines times! The presenters will report the results of their systematic reviews as the recommendations are undergoing vetting First up: Seizure prophylaxis
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@AJWPharm
Andy Webb
4 years
Do you ever have those days at work where despite all signs showing you're doing Just Fine and your team is grateful for your input but you just can't shake the feeling you're not doing well enough? Yea me too
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@AJWPharm
Andy Webb
3 years
When I round with the stroke team and we enter the room to examine the patient, I'm no help with the neuro exam so I give myself another job - open the blinds and update the date/day of the week on the whiteboard if it hasn't already been done No delirium on my watch ☀️
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@AJWPharm
Andy Webb
5 months
Well this is neat! Honored to have my @SCCM_CPP presentation at @SCCM 2024 selected as one of the Best of SCCM Congress
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@AJWPharm
Andy Webb
2 years
Every damn day
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@AJWPharm
Andy Webb
5 years
The past few weeks I saw lots of pictures of poster presentations which means I also saw lots of pictures of pie charts. Thought I'd throw together a little data viz 101 on how pie charts are usually a poorly efficient way visualize your data
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@AJWPharm
Andy Webb
4 months
I'll do a brief thread on my thoughts, mostly because much of what is reported is not new and others have shared similar thoughts ANNEXA-I randomized mostly sICH patients w GCS >7 w/i 15 h of last DOAC to AA vs usual care. Here is the treatment algo, from the protocol:
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@AJWPharm
Andy Webb
4 months
Oh my... The time has arrived! ANNEXA-I has been published Time to dig in...
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Andy Webb
3 years
This is a PSA to please use the Page Break function in Word so you don't have to hammer the enter key to get things to a new page and ruin my beautiful formatting thank you for coming to my TED talk
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@AJWPharm
Andy Webb
5 years
*Team trying to figure out why a patient's wound keeps getting infected* Me: "Does he have any pets?" Team: "I have no idea" Patient: "Oh yea, I let my dogs lick my wounds all the time" Pharmacists: good for more than just drugs
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@AJWPharm
Andy Webb
4 years
Ok this might be insane for a resident but there's a real chance I might adopt this absolute nugget of a pupper
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@AJWPharm
Andy Webb
3 years
Evaluating your own CE to claim CE credit
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@AJWPharm
Andy Webb
3 years
ICU admission order sets really be like "Welcome to the ICU! Here's 3 laxatives"
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@AJWPharm
Andy Webb
1 year
I think we're safe for now
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@AJWPharm
Andy Webb
5 years
@AliRaja_MD Tacrolimus was named after the area in Japan it was discovered, Tsukuba Tsukuba mACROlide IMmUnoSuppresant
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@AJWPharm
Andy Webb
2 years
I am mostly only good for antibiotic dosing and med chem fun facts
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@AJWPharm
Andy Webb
1 month
Can droxidopa help patients get off pressors? As a norepi prodrug, it may have an edge over our traditional agent of choice, midodrine. In our new multicenter study, we our experience adding droxidopa in 30 persistently hypotensive patients on pressors
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@AJWPharm
Andy Webb
5 years
Excited to present my quality improvement project on shortening the duration of antibiotic prophylaxis after neurosurgical drain placement at @VizientInc ! Poster 240A - come by! #ASHP19
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@AJWPharm
Andy Webb
2 years
There are dozens of antibiotics out there to treat infections But few are quite as time-tested and reliable as vancomycin Here are 11 reasons why you might as well just go ahead and start your patient on vancomycin 👇
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@AJWPharm
Andy Webb
4 years
Honored that my first published article has made it on to the @AJHPOfficial Top 25 Articles of 2020! Important area of research deserving of more attention.
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@AJWPharm
Andy Webb
1 year
When the handoff is to watch the renal function closely
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@AJWPharm
Andy Webb
4 years
Buying a bag of chocolate chips: This will be great when I get the inspiration to bake Owning a bag of chocolate chip: This is a suitable replacement for all three meals and applicable snacks
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@AJWPharm
Andy Webb
3 years
Young patient started on vanc and 2-point PK shows calculated peak of ~120 & trough of ~4 w/ T1/2 of 1.5h and Vd of ~8L. Seems wrong. Repeat levels and same result. Change to continuous infusion of 3.5g/24h (145mg/h / Vd of 8L = Cpss of ~18 mg/L) First level on CI? 17.4
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@AJWPharm
Andy Webb
4 years
Call me extra but I'm pretty sure if a collect a few more I unlock the Infinity Patagonia and white coats will be banished forever
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@AJWPharm
Andy Webb
3 years
Taught my team about CysC today - CrCl >120 mL/min but vanc >20 with 15mg/kg q12? Cystatin C tells a different story. The attending's reaction - "why don't we use this more??" Thanks to @erin_barreto and co for teaching me there's more to renal function than just creatinine
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@AJWPharm
Andy Webb
2 years
See you all in San Francisco! @SCCM_CPP @SCCM_Neuro
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@AJWPharm
Andy Webb
5 years
The inventor of the selegiline patch named the product after his two kids Emily and Sam - Emsam!
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@AJWPharm
Andy Webb
4 years
Residency program Twitter accounts are all the rage these days - read about @JasonMordino , @DanielleTBurton , @garrett_schramm , and my strategy for success for running a successful account!
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