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npj Digital Medicine Profile
npj Digital Medicine

@npjDigitalMed

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Open access @NaturePortfolio journal for the #DigitalHealth community, publishing research, reviews & comments. Tag us & tweet your work with @npjDigitalMed .

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Joined February 2022
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@npjDigitalMed
npj Digital Medicine
25 days
Missed our podcast episode with The Medical Futurist @Berci and @Yosra_Mekki ? Feel free to play back the recording below:
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@npjDigitalMed
npj Digital Medicine
11 months
This study develops a generative clinical LLM using 277 billion words of text and up to 20 billion parameters. The model improves biomedical natural language processing, generates synthetic clinical text, and passed Turing test in writing clinical notes.
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@npjDigitalMed
npj Digital Medicine
1 year
In this perspective, @Berci & @EricTopol discuss the regulation of GPT-4 & generative #ArtificialIntelligence in medicine... balancing the exciting + transformative potential, but ensuring safety, maintaining ethical standards, & protecting privacy.
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@npjDigitalMed
npj Digital Medicine
1 year
Foundation models (FMs) such as #ChatGPT have the potential to revolutionize healthcare. But what's hype and what's real? This review from a team in @StanfordMed includes 84 clinical FMs + proposes an evaluation framework better suited to assess value.
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@npjDigitalMed
npj Digital Medicine
2 years
It is important to ensure #digitalhealth does not accelerate #healthdisparities . @SafiyaMD et al. from @nyugrossman present this framework inc. key digital determinants of health, from individual to societal, to understand the impact on health #equity .
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@npjDigitalMed
npj Digital Medicine
2 years
We are delighted to welcome @girish_nadkarni to the #npjDigitalMed Editorial Team. Girish brings a wealth of #DigitalHealth and #Nephrology expertise to our Editorial Board Member team.
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@npjDigitalMed
npj Digital Medicine
9 days
This study developed an open-source tool using a LLM to extract important medical information from clinical text, focusing on decompensated #LiverCirrhosis . The tool identified liver cirrhosis from free text with 100% sensitivity and 96% specificity, and showed strong results
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@npjDigitalMed
npj Digital Medicine
7 months
Your weekend read editorial: Discussing the importance of shifting the focus towards clinically relevant outcomes, when adopting #ArtificialIntelligence tools, the ecosystem required for AI to succeed in health, & the human aspect of #healthcare .
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@npjDigitalMed
npj Digital Medicine
9 days
This article introduces ETHOS, an AI tool that uses advanced #MachineLearning to predict future health outcomes based on patient records, without needing labelled data or model tuning. This tool can simulate different treatment options, helping improve patient care & reduce
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@npjDigitalMed
npj Digital Medicine
1 year
Are large language models (LLMs) safe for use in medicine? In this study led by @OmiyeTofunmi & @RoxanaDaneshjou , the authors found that four different LLMs had outputs that perpetuated false race-based medicine.
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@npjDigitalMed
npj Digital Medicine
1 year
(1/4) Can AI help surgeons improve their skills? We are delighted to share a trio of articles published across @NaturePortfolio covering AI-based assessment of surgery skills, authored by @DaniKiyasseh and colleagues. All articles are fully open access 🔓
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@npjDigitalMed
npj Digital Medicine
3 months
A meta-meta-analysis shows e- & m-Health interventions improve #physicalactivity , sedentary behavior, #diet , bodyweight & #sleep . These scalable interventions offer significant benefits across diverse populations, enhancing public health.
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@npjDigitalMed
npj Digital Medicine
6 months
A curated database of @US_FDA -cleared #ArtificialIntelligence products for medical imaging indicates a high prevalence of triage systems, variability in basic output characteristics, and often limited #explainability of AI predictions.
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@npjDigitalMed
npj Digital Medicine
2 years
A comprehensive review of natural language processing over the past 15 years from a team in the UK. NLP budgets from research funding now are 80x that from 2007-10, yet there is still much to do in this field to realise its potential.
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@npjDigitalMed
npj Digital Medicine
1 year
Of 4 collaboration strategies to deploy #AI for the diagnosis of ARDS from chest XR, the most accurate is to allow AI review the XR first & defer to the physician if uncertain. 79% of cases were decided by AI - significantly reducing physician workload.
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@npjDigitalMed
npj Digital Medicine
6 months
"Data have become the most valuable commodity in health care, but questions remain about whether there will be an #AI 'revolution' or 'evolution' in health". This perspective article discusses action areas & recommendations to achieve AI's full potential.
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@npjDigitalMed
npj Digital Medicine
6 months
Generative #ArtificialIntelligence can create synthetic patient data that closely mimics disease biology, treatment response & long-term survival compared to real clinical trial cohorts. Synthetic patient data may augment control groups in trial designs.
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@npjDigitalMed
npj Digital Medicine
2 years
Gestational age estimation has an error of +/- 2 weeks in late #pregnancy . The application of this #machinelearning model using only ultrasound image analysis reduces this error to 3 + 4 days in the 2nd & 3rd trimesters representing a major step forward.
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@npjDigitalMed
npj Digital Medicine
6 months
With advancements in data science & #AI , the concept of #DigitalTwin for Health holds immense potential. This scoping review explores its promising applications, paving the way for a collaborative global effort in healthcare innovation.
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@npjDigitalMed
npj Digital Medicine
2 years
What can we learn from how you type on your phone? This study shows that it’s possible to track and predict fluctuations in people’s mental health status based on how they type on their phone with nearly 95% accuracy.
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@npjDigitalMed
npj Digital Medicine
2 years
New article! Read Making machine learning matter to clinicians: model actionability in medical decision-making in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
2 years
Introducing @drjessilyn , Jessilyn joined us as an Associate Editor in March 2021 and is one of our longest-serving Associate Editors. Jessilyn is highly experienced in assessing manuscripts focused on digital biomarkers and machine learning.
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@npjDigitalMed
npj Digital Medicine
6 months
New article! Read Self-supervised learning for human activity recognition using 700,000 person-days of wearable data in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
2 years
This perspective from @JohnTorousMD , @arieldora + @ftbourgeois gives a useful outline of the structure + challenges in the SaMD regulatory landscape with @US_FDA incl. examples. Encouraging work is happening, but plenty more to be done... #DigitalHealth
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@npjDigitalMed
npj Digital Medicine
1 year
This Perspective, written by one of our previous Editors-in-Chief, @EricTopol , and @Berci continues to attract readers and was our 🏆 top @altmetric article for July 2023.
@NaturePortfolio
Nature Portfolio
1 year
A Perspective in @npjDigitalMed argues that regulatory oversight should assure medical professionals and patients can use large language models and AI without causing harm or compromising their data or privacy and offers recommendations to regulators.
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npj Digital Medicine
7 months
Smartphones & #wearables transform health monitoring. However, bias in digital health studies and algorithms arises from underrepresented datasets. This @DukeU team explore device ownership, reasons for use, & willingness to share data for research.
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npj Digital Medicine
1 year
Using a phone app to monitor wounds for infection after surgery... In this multi-centre pilot, 200 patients felt the app improved almost every aspect of their wound care after surgery including usefulness, ease of use, reliability of tech, & satisfaction.
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@npjDigitalMed
npj Digital Medicine
9 months
Large language models show promise for identifying social determinants of health in clinic notes, with smaller, fine-tuned models showing more robust performance & less potential bias than ChatGPT-family models.
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@npjDigitalMed
npj Digital Medicine
2 years
A single approach that can recognise walking with a variety of body-worn devices regardless of walking style, sensor location and configuration is presented in this paper to estimate walking time, cadence and step count.
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@npjDigitalMed
npj Digital Medicine
10 months
Large language models can rapidly phenotype patients with no manual annotation. This study reports on the evaluation of a publicly available LLM for zero-shot phenotyping using clinical notes with a proof-of-concept in postpartum hemorrhage.
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@npjDigitalMed
npj Digital Medicine
1 year
We would like to welcome Prof. @girish_nadkarni from @IcahnMountSinai to our Associate Editor team. Girish is specialized in AI and emerging technologies in medicine.
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@npjDigitalMed
npj Digital Medicine
1 year
Our June Reviewer of the Month is @kdpsinghlab ! On peer review, Karandeep comments: "With all the rapid innovations happening right now in the space of AI & large language models, it's more important than ever to separate hype from reality."
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@npjDigitalMed
npj Digital Medicine
1 year
Can synthetic data improve AI models? In this paper, a generative model for synthesizing mixed-type timeseries health records, including physiological signals, lab results, & medication uses, improved the downstream applications of AI in critical care.
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@npjDigitalMed
npj Digital Medicine
10 months
This team from @cerebral built a #MachineLearning system to identify chat messages from patients experiencing #mentalhealth crises. When deployed in a national telehealth network it reduced response times to patients in crisis from 10 hours to <10 mins.
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@npjDigitalMed
npj Digital Medicine
2 years
Introducing @JohnTorousMD , John joined us as an Associate Editor in November 2021. John is highly experienced in assessing manuscripts focused on digital psychiatry and mental health.
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@npjDigitalMed
npj Digital Medicine
8 months
Can a novel #DeepLearning algorithm to predict #sepsis in the emergency department improve care? Researchers from @UCSDHealth show proper implementation of the model can save lives of sepsis patients and improve quality metrics.
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@npjDigitalMed
npj Digital Medicine
1 year
This perspective proposes a framework to improve computational phenotyping by enhancing accessibility & usefulness. The authors present an example focussing on easy adoption, cross-task reusability, and clinical phenotyping algorithm development support
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@npjDigitalMed
npj Digital Medicine
2 years
We are thrilled to welcome Professor @adamdunn from @Sydney_Uni to our Associate Editor team! Adam brings a wealth of public health & clinical informatics expertise, with a particular interest in online misinformation & health behaviors.
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@npjDigitalMed
npj Digital Medicine
8 months
Mitigating the 'black box' of AI: LLMs can imitate diagnostic reasoning strategies when solving clinical cases & provide an interpretable means to assess if the generated answer is true/false based on the diagnostic reasoning's factual & logical accuracy.
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@npjDigitalMed
npj Digital Medicine
1 year
📢 Open for submissions, our new collection, Clinical Applications of AI in Mental Health Care. This collection is in collaboration with @npjMentalHealth & is Guest Edited by Eric Kuhn, @MauriceMulvenna , Raymond Bond, & @JohnTorousMD .
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@npjDigitalMed
npj Digital Medicine
10 months
New article! Read A medical multimodal large language model for future pandemics in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
4 months
Germany's DiGA program was the first to implement #DigitalTherapeutics on a large scale. Three years later, increased usage and accumulated experience have prompted regulatory changes that expand the program's scope.
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@npjDigitalMed
npj Digital Medicine
9 months
This umbrella review summarizes 48 #systematicreviews on effectiveness of app-based health interventions within patient populations published from 2013-23. Find out how skewed the evidence is towards some indications & where quality remains suboptimal:
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@npjDigitalMed
npj Digital Medicine
7 months
Claims about how #AI will increase efficiency are prominent but flawed, because they are based on studies of accuracy. Accuracy ≠ efficiency... We must remain conscious that an accurate model does not guarantee efficiency gains & workload reduction.
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@npjDigitalMed
npj Digital Medicine
9 months
A novel wearable-sensor dataset of healthcare workers from @sujnagaraj et al. reveals high levels of inter- & intra-individual heterogeneity in stress - an important step towards characterizing #stress in individuals.
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@npjDigitalMed
npj Digital Medicine
2 years
Using datasets of EHR + #echofirst , @David_Ouyang et al. found confounders mediate AI prediction of demographics. Unaccounted confounders provide a substantial amount of the information in “predicting race” and performance drops when balancing covariates.
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@npjDigitalMed
npj Digital Medicine
1 year
Breaking news 💥 Our Guest Editor Raymond Bond announces the launch of our new collection call for papers, Clinical applications of AI in mental health care. This is a collaboration with new launch @Nature_NPJ journal @npjMentalHealth .
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@npjDigitalMed
npj Digital Medicine
1 year
Advancing EHR-based deep phenotyping... An algorithm for mapping clinical Observational Medical Outcomes Partnership (OMOP) vocabularies to @OBOFoundry ontologies to help systematically identify undiagnosed patients who might benefit from genetic testing.
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@npjDigitalMed
npj Digital Medicine
1 year
A #deeplearning model, the Stanford Estimator of Electrocardiogram Risk, predicts long-term risk of #cardiovascular mortality and disease from a single ECG with performance better than current standard risk screening tools.
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@npjDigitalMed
npj Digital Medicine
24 days
Scaling AI for surgical guidance to operating rooms globally remains a major challenge, especially resource-limited settings. These authors describe a novel equipment-agnostic #MachineLearning pipeline to enable real-time deployment to any edge device.
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@npjDigitalMed
npj Digital Medicine
2 years
New editorial from our EiC @jkvedar and colleagues at @harvardmed . This piece focuses on promoting #RacialEquity in #DigitalHealth and suggests applying a framework to 3 areas within digital medicine 1⃣ #AI applications 2⃣ #Wearables 3⃣ #Telehealth
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@npjDigitalMed
npj Digital Medicine
2 years
Health data justice: "the study and use of health-related data in ways that aim to redress the exclusions of structurally marginalized communities from systems of health care and public health…" An interesting piece from @jayshaw29 & @sharifasekalala .
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@npjDigitalMed
npj Digital Medicine
1 year
Artificial intelligence for diagnosing psychological & neuro disorders is frequently studied in labs but rarely implemented clinically. This review outlines the biological, technical & institutional barriers to making diagnostic AI a reality in hospitals.
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@npjDigitalMed
npj Digital Medicine
6 months
Deep learning of ECGs can help identify patients with hidden #atrialfibrillation better than predictions based on clinical risk factors & echo measurements. This may offer additional opportunities to guide patient screening & support early intervention.
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@npjDigitalMed
npj Digital Medicine
16 days
Our most recent News & Views article examines the ethical tension between "selective deployment," where AI is used only for subgroups it performs well in, and "equitable deployment," which aims for fair performance across all groups. This article emphasizes the need for better
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@npjDigitalMed
npj Digital Medicine
1 year
An #RCT led by @JRGolbus & @bnallamo from @umichCVC with 220 participants showed that contextually-tailored text messages from wearable devices may improve physical activity for some cardiac rehab participants but displayed no sig. difference at 6 months.
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@npjDigitalMed
npj Digital Medicine
2 years
Surgeons with different experience levels use different surgical gestures in robotic-assisted surgery. These gestures were predictive of 1-year postop function, suggesting gestures could objectively measure surgical performance + outcomes.
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@npjDigitalMed
npj Digital Medicine
6 months
Exploring evaluation metrics for health #Chatbots . What is the current norm? What are their weaknesses? This perspective also introduces a set of user-centered evaluation metrics, grouped into accuracy, trustworthiness, empathy, & computing performance
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@npjDigitalMed
npj Digital Medicine
4 months
Many #MachineLearning & AI algorithms struggle to generalize, preventing responsible deployment. @GSK AI/ML and @CC4AIM use a real-world case study to look at how selective predictions might be implemented technically & explore ethical implications.
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@npjDigitalMed
npj Digital Medicine
5 months
Studies of #AI in medicine may overestimate accuracy to new situations by 20%. Models learn hidden biases in X-rays, ECGs, clinical notes etc. instead of real disease markers. This study proposes a solution for inc. reliability in reporting of results.
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@npjDigitalMed
npj Digital Medicine
1 year
New article! Read Generating synthetic mixed-type longitudinal electronic health records for artificial intelligent applications in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
2 years
Exciting new work out in @npjdigitalmed by @DrVeronikaCH (prof @ITUkbh ) & @GaelVaroquaux (cofounder @scikit_learn ) proposes several opportunities for data scientists & researchers to advance the field of machine learning-based medical imaging analysis.
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@npjDigitalMed
npj Digital Medicine
2 years
Christmas Catch-Up: Using a #digitalhealth platform to capture patient reported outcomes every 3 days after cardiac surgery showed that patient perception of recovery varies substantially, offering more granular info than conventional outcome metrics.
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@npjDigitalMed
npj Digital Medicine
11 months
Multicenter EHR data from >234k adult non-cardiac surgical patients is used to predict maximum pain after surgery. This #MachineLearning model prospectively outperformed clinicians, & can identify comorbidities that drive postoperative pain.
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@npjDigitalMed
npj Digital Medicine
2 years
Factors inc. sociodemographics, depression severity, phone status & app usage behavior could be linked to long-term participant retention in remote mobile health studies... Findings from a large European multinational remote digital study for #depression .
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@npjDigitalMed
npj Digital Medicine
2 years
New article! Read The evolution of digital health technologies in cardiovascular disease research in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
1 month
New article! Read Digital biomarkers for precision diagnosis and monitoring in Parkinson’s disease in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
1 year
Building an AI-based 'clock' of physical activity & sleep during pregnancy from >1000 participants' wearable data. This model uses just a smartwatch to predict gestational age. Deviations from this 'clock' are very strongly associated with preterm birth.
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@npjDigitalMed
npj Digital Medicine
11 months
📢 Announcing our new collection🌍Harnessing digital health technologies to tackle climate change and promote human health🌍 Guest Edited by @JRedHeart @KariceHyun & @GeorgiaKatec . Deadline to submit 30 April 2024. More info🔗
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@npjDigitalMed
npj Digital Medicine
3 months
We’re excited to announce the first episode in the 'Who’s Who in Our 'X' Community?' series. We highlight @StanfordBDHG ’s efforts towards digital health education with @vishnuravi @PSchmiedmayer @DrAalami @StanfordSpezi . Mark your calendars for July 17th 12 pm EST, 9 am PDT.
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@npjDigitalMed
npj Digital Medicine
3 months
What are some educational initiatives that you know of designed to educate medical or CS/Eng students about digital health? We’re starting a series to amplify such efforts. Tag them below!
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@npjDigitalMed
npj Digital Medicine
2 years
Another for our #digitalsurgery readers… This review explores current #computervision techniques applied to minimally invasive surgery, the clinical applications and discusses the challenges to wider adoption.
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@npjDigitalMed
npj Digital Medicine
2 years
New article! Read A large language model for electronic health records in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
18 days
Large language models ( #LLMs ) can effectively summarize medical evidence, but proprietary LLMs often lack transparency and create vendor dependency. This study showed that fine-tuning open-source LLMs significantly improves their performance, bringing some models, like LongT5,
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@npjDigitalMed
npj Digital Medicine
3 months
We love nothing more than a good author thread on their paper! Here is @JoschkaHalt describing his paper with @RobRanisch discussing the ethical landscape surrounding the current deployment of LLMs in medicine and healthcare.
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@JoschkaHalt
Joschka Haltaufderheide
3 months
1/ How are #ChatGPT and other #LLMs used in #Medicine ? And what are the ethical implications? We say: It’s a social experiment unfolding right in front of us! Check out @robranisch ‘s and my new paper in @npjDigitalMed Let me give you a quick tour
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@npjDigitalMed
npj Digital Medicine
1 year
New article! Read An integrative review on the acceptance of artificial intelligence among healthcare professionals in hospitals in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
1 year
Measures derived from @fitbit + patient characteristics are used to train #MachineLearning models to detect abnormal recovery in children after appendectomy, with results supporting the use of remote monitoring for early detection of postop complications.
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@npjDigitalMed
npj Digital Medicine
1 year
This perspective provides an overview of the misalignments of current #ArtificialIntelligence fairness research, with discussion on the practical clinical concerns & the obstacles to AI fairness adaptation. #AIfairness
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@npjDigitalMed
npj Digital Medicine
2 years
New article! Read A “one-size-fits-most” walking recognition method for smartphones, smartwatches, and wearable accelerometers in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
7 months
When adopting #AI in the real world, the trade-off between performance & cost-effectiveness needs examination. This case study on real-world #diabetic retinopathy screening in China suggests the most accurate AI may not be the most cost-effective.
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@npjDigitalMed
npj Digital Medicine
2 years
Huge congratulations to our Associate Editors @JohnTorousMD and Dr. John Rogers who made the @Clarivate Highly Cited Researchers 2022 list. #HighlyCited2022
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@npjDigitalMed
npj Digital Medicine
7 months
Smartphone typing dynamics and accelerometery was predictive of motivation levels & the ability to feel pleasure in suicidal ideation for people assigned female sex at birth in this study from @LoranKnol et al. #mentalhealth
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@npjDigitalMed
npj Digital Medicine
2 years
Introducing @KariceHyun , Karice joined us as an Associate Editor in June last year and is highly experienced in assessing biostatistics methodology.
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@npjDigitalMed
npj Digital Medicine
1 year
New article! Read Applying machine learning to consumer wearable data for the early detection of complications after pediatric appendectomy in npj Digital Med
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@npjDigitalMed
npj Digital Medicine
8 months
A large language model fine-tuned on clinical notes to enhance Diagnosis-Related Group (DRG) assignment - a system to classify hospital cases. This model showed superior performance compared to prior models in the task of DRG prediction.
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@npjDigitalMed
npj Digital Medicine
1 year
Digital health interventions vary widely and control groups used to test the effects of these interventions are even more variable. This perspective proposes names for 11 commonly used control conditions & discusses the scientific implications of each.
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@npjDigitalMed
npj Digital Medicine
2 years
Clinicians perceive #MachineLearning as an augmentation rather than substitute to their clinical practice. This qualitative analysis by @KatharineEHenry , @suchisaria et al. explored opinions of clinicians working with a ML-based sepsis warning system...
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@npjDigitalMed
npj Digital Medicine
7 months
It's time for another weekend read editorial... This week, exploring #GenAI with Marium Raza, @KaushikVenkates & @jkvedar . Building on a recent framework from @MichaelWornow et al. this article includes an evaluation checklist for GenAI applied to EHRs.
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@npjDigitalMed
npj Digital Medicine
2 years
An interesting perspective this week discussing the #regulatory implications of changes from the EU's MDR regarding #digitalhealth apps.
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@npjDigitalMed
npj Digital Medicine
3 months
Using computer vision to transform smartphone videos into highly accurate tools for tremor analysis to rival gold-standard equipment... These digital biomarkers provide added value for assessing DBS outcomes in patients with essential tremor.
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@npjDigitalMed
npj Digital Medicine
2 months
Watch this clip to discover why @AjhungMD , a pioneer in medical AI 🌟, chose npj Digital Medicine to publish his research on bias mitigation, surgical AI, and more:
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@npjDigitalMed
npj Digital Medicine
1 year
A #MachineLearning pipeline to help identify skin tone representation in medical education textbooks. Notable findings that dermatology textbooks are biased with brown & black skin tone (Fitzpatrick V-VI) images constituting only 10.5% of all skin images
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@npjDigitalMed
npj Digital Medicine
1 year
This study on #AI implementation finds that causal inference models, contextualized explanations, and ambidexterity between exploration versus exploitation mindsets can help bridge clinicians’ needs and developers' goals to solve the XAI conundrum.
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@npjDigitalMed
npj Digital Medicine
1 year
We have 3⃣ exciting open collections welcoming submissions, led by expert Guest Editors. 📌 Digital Technologies for Parkinson's Disease 📌 Clinical applications of AI in mental health care 📌 Regulated digital medical products Find out how to submit:
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@npjDigitalMed
npj Digital Medicine
2 years
Data from wearables can characterize daily physical activity and its change over time in persons with Amyotrophic Lateral Sclerosis, and were significantly associated with clinical patient reported outcome measures… a potential future digital endpoint?
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