Small-fiber
#neuropathy
beginning within a month of
#COVID
-19 onset may be common in long-COVID, though larger investigations are needed. Learn more:
#NeuroTwitter
Novakovic-White et al provide a literature review of clinical, radiographic and anatomical features of posterior circulation ischemia and systematic review of the literature on the management of basilar artery occlusion and associated outcomes.
#Neurology
This study provides Class II evidence that sustained increase in overall regular physical activity levels in patients with early
#Parkinson
disease was associated with slower decline of several clinical parameters.
#Neurology
#NeuroTwitter
In this study, long-term regular physical activity levels and exercise habits were
strongly associated with a better clinical course of
#Parkinson
disease, with each
type of physical activity having different effects. Learn more:
#NeuroTwitter
In patients with nonvalvular atrial fibrillation who develop ischemic
#stroke
despite taking direct oral anticoagulants (DOACs), switching to warfarin or an alternate DOAC may increase the risk of recurrence. Learn more:
#NeuroTwitter
Novakovic-White et al provide a literature review of clinical, radiographic and anatomical features of posterior circulation ischemia and systematic review of the literature on the management of basilar artery occlusion and associated outcomes.
#Neurology
Extensive brainstem and striatal involvement are rare manifestations of neuropsychiatric systemic lupus erythematosus (NPSLE). Learn more in this
#NeurologyRF
Teaching
#NeuroImage
article:
Tuberculous Meningitis or
#Neurosarcoidosis
—a Diagnostic Quandary: From the National Multiple Sclerosis Society Case Conference Proceedings:
Illustration by Jill K. Gregory, CMI, licensed under CC BY-NC-ND.
#NeuroTwitter
A 78-year-old healthy woman presented with abulia, aphasia, and echopraxia for 1 week. Learn more in this Teaching NeuroImage article:
#NeurologyRF
#NeuroTwitter
This study demonstrates that T2-lesions in MOGAD usually resolve within 1 year and follow-up MRI at 6–12 months showing resolution of all or most T2-lesions can help support a
#MOGAD
diagnosis over competing etiologies.
#NeuroTwitter
A woman is started on haloperidol for schizophrenia. Ten days later, she develops rhythmic vertical movements of the mandible (video). Haloperidol is replaced with olanzapine and the movements improve within days.
According to this study, dexamethasone doses exceeding 4 mg with 10 mg metoclopramide IV are unlikely to provide extra benefits in patients with migraine in the emergency department. Read the article:
#NeuroTwitter
Tuberculous Meningitis or
#Neurosarcoidosis
—a Diagnostic Quandary: From the National Multiple Sclerosis Society Case Conference Proceedings:
Illustration by Jill K. Gregory, CMI, licensed under CC BY-NC-ND.
#NeuroTwitter
Ictal asystole is a rare condition associated primarily with temporal lobe epilepsy that can cause syncope, falls, and head trauma. Read about a severe case in this Pearls & Oy-sters article:
#NeurologyRF
A 22-year-old woman presented with bilateral arm shaking and altered mental status. Neurologic examination found decreased level of consciousness and upper extremity spasticity. Learn the diagnosis:
#NeurologyRF
This study sought to investigate the association between white matter lesions and CSF biomarkers of neuroinflammation and their effects on cognition in a population without
#dementia
. Read to learn more:
#NeuroTwitter
According to this study, DAT imaging is a useful diagnostic tool in the differential diagnosis of parkinsonism, although clinicians should be aware of its diagnostic properties and limitations. Learn more:
#Neurology
#NeuroTwitter
A 38-year-old woman with uncontrolled type 1 diabetes was admitted for diabetic ketoacidosis (DKA). Serum sodium was 139. Upon correction of DKA, she developed acute quadriparesis.
#NeurologyRF
Teaching Video NeuroImage: Bilateral Horizontal Gaze Palsies With Vertical Ocular Dysmetria From a Demyelinating Lesion of the Pontine Tegmentum
#NeurologyRF
Though rapid correction of serum sodium is the most common cause of central pontine myelinolysis, rapid changes in serum glucose and urea levels can be covert culprits. Learn more:
#NeuroTwitter
#NeurologyRF
The “shrimp sign” is a reliable indicator of infratentorial progressive multifocal leukoencephalopathy in patients with cerebellar ataxia. Learn more in this Teaching NeuroImage article:
#NeurologyRF
#NeuroTwitter
Extensive brainstem and striatal involvement are rare manifestations of neuropsychiatric systemic lupus erythematosus (NPSLE). Learn more in this
#NeurologyRF
Teaching
#NeuroImage
article:
This Clinical/Scientific Note reports a case of fatal super-refractory status epilepticus associated with amyloid-related imaging abnormalities (
#ARIA
):
#NeuroTwitter
According to this study, an algorithm using clinical and imaging features can differentiate stroke-like episodes due to MELAS from acute ischemic strokes. This article is free to read:
#NeuroTwitter
#NeuroGenetics
This review summarizes the current understanding of poststroke epileptogenesis, its risks, prognostic models, prophylaxis, and strategies for secondary prevention of seizures and suggests strategies to advance research:
#Neurology
#NeuroTwitter
Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage: Location, Distribution Patterns, Infarct Load, and Effect on Outcome
#NeuroTwitter
A 12-year-old otherwise normal girl presented with progressive dystonia and spasticity in bilateral lower limbs. Brain MRI revealed mineral deposition.
#NeuroTwitter
#NeurologyRF
This study provides Class II evidence that among those aged 65 years or older, statin initiation was associated with a reduced risk of
#Alzheimer
disease, especially in the presence of an APOE-e4 allele:
Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage: Location, Distribution Patterns, Infarct Load, and Effect on Outcome
#NeuroTwitter
Unilateral primary angiitis of the CNS is a rare unihemispheric disease characterized by an indolent course and seizures, recognition of which is critical to accurate diagnosis. Learn more in this
#NeurologyRF
Teaching
#NeuroImage
article:
This case highlights an unusual presentation of severe MOGAD, emphasizes the potential benefit of plasma exchanges in severe MOGAD cases refractory to steroid treatment, and demonstrates how assessment of CSF IL-6 may help guide treatment decisions:
A study by Ikeguchi et al suggests that ovarian teratoma may trigger the development of AQP4-IgG–seropositive neuromyelitis optica spectrum disorder (
#NMOSD
).
#NeuroTwitter
#Neurology
A 72-year-old woman with hypertension and hyperlipidemia develops altered mental status, left hemiparesis, and right gaze preference after a percutaneous coronary angioplasty. Her head CT without contrast is shown. She recovers spontaneously after 2 days. What is your diagnosis?
This study provides Class II evidence that the Boston criteria v2.0 accurately distinguishes people with cerebral amyloid angiopathy (CAA) from those without CAA:
#NeuroTwitter
CLIPPERS can induce vasogenic edema by damaging vascular endothelial cells through T-cell activation, representing a rare cause of obstructive hydrocephalus. Learn more:
#NeuroTwitter
#NeuroImage
This case illustrates an atypical presentation of NMOSD and the importance of looking for syndromes, such as the syndrome of inappropriate antidiuretic hormone secretion (SIADH):
#NeurologyRF
#NeuroTwitter
CADASIL and CAA-RI share similarities in clinical presentation, vascular pathology, and imaging findings. This Teaching NeuroImage article highlights the challenge of distinguishing between the two:
#NeurologyRF
#NeuroTwitter
This study's findings suggest that the cerebellum is the central hub of a network commonly connected to structural and metabolic abnormalities in essential tremor:
#NeuroTwitter
This study sought to investigate the association between white matter lesions and CSF biomarkers of neuroinflammation and their effects on cognition in a population without
#dementia
. Read to learn more:
#NeuroTwitter
Take the latest
#NeurologRF
🧠 quiz!
A 32-year-old male without vascular risk factors presented with acute onset vertigo, swallowing dysfunction, and right-sided weakness. Figure: Brain MRI DWI
(Associated article: )
Recent advances in the diagnosis and treatment of
#neurosarcoidosis
include updated diagnostic criteria and mounting evidence supporting a role of TNF-alpha inhibition for aggressive and/or refractory cases. Learn more:
#NeuroTwitter
This case highlights an unusual presentation of severe MOGAD, emphasizes the potential benefit of plasma exchanges in severe MOGAD cases refractory to steroid treatment, and demonstrates how assessment of CSF IL-6 may help guide treatment decisions:
A 44‐yo man with alcohol use disorder presented with unresponsiveness. Toxicology was positive for cocaine and fentanyl. Imaging findings suggested CHANTER syndrome, a rare radiographic pattern observed in acute intoxication. Learn more:
#NeurologRF
This Clinical/Scientific Note reports a case of fatal super-refractory status epilepticus associated with amyloid-related imaging abnormalities (
#ARIA
):
#NeuroTwitter
Medial medullary lamina-sparing mineral deposition is a characteristic feature of mitochondrial membrane protein-associated neurodegeneration (MPAN). Learn more in this Teaching NeuroImage article:
#NeurologyRF
#NeuroTwitter
Dramatic Response to Anti-IL-6 Receptor Therapy in Children With Life-Threatening Myelin Oligodendrocyte Glycoprotein-Associated Disease:
#NeuroTwitter
This case highlights an unusual presentation of severe MOGAD, emphasizes the potential benefit of plasma exchanges in severe
#MOGAD
cases refractory to steroid treatment, and demonstrates how assessment of CSF IL-6 may help guide treatment decisions:
Occipital lobe
#seizures
are a rare but characteristic manifestation of hyperglycemia. Glycemic control generally results in their resolution, emphasizing the importance of prompt diagnosis. Learn more in this Teaching NeuroImage article:
#NeurologyRF