Adrian H @Adrian_H Twitter profile

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Adrian H

@Adrian_H

4 years

@HctPGuidance You‘d be worried that somebody might get the impression that it’s all made up.

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Adrian H

@Adrian_H

1 year

@SteveMatthews12 @JohnArnoldFndtn the ones that are on the shelf.. they keep the stuff that works behind the counter

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Adrian H

@Adrian_H

4 years

@PreetBharara Teen Vogue has much better writing anyway.

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Adrian H

@Adrian_H

4 years

@JessicaHuseman what are you doing in an ihop in the middle of a pandemic

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Adrian H

@Adrian_H

2 years

Just got served in the $SAVA Cassava v Bredt lawsuit while at my poster discussing Simufilam science and binding at the #ctad22 conference. #scienceintegrity

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Adrian H

@Adrian_H

6 months

"Because the Court finds that the majority of the defendants’ statements were protected under the First Amendment as statements of opinion or scientific debate, and that the fraction of statements that were adequately alleged to be defamatory were not published with actual

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Adrian H

@Adrian_H

3 months

what's this, a DOJ indictment? $SAVA

Professor Charged for Operating Multimillion-Dollar Grant Fraud

A federal grand jury in the District of Maryland returned an indictment yesterday charging a Pennsylvania man for defrauding the U.S. National Institutes of Health (NIH) of approximately $16 million...

www.justice.gov

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Adrian H

@Adrian_H

3 years

Cassava Sciences is a shambolic scientific charade. We have assessed virtually every aspect of Cassava's programs, & reveal a pattern of deliberate, coordinated misconduct. Our letter to FDA & slides: $SAVA @DRnotaDR @jesse_brodkin @PatricioMarceso

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Adrian H

@Adrian_H

3 months

@BennettTomlin there really ought to be a door at the front that has to be closed for it to run

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Adrian H

@Adrian_H

2 months

$SAVA

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Adrian H

@Adrian_H

2 months

$SAVA

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Adrian H

@Adrian_H

3 years

@michaelmina_lab agree in theory, but "quickly" is something like 60-90 days, and the original vaccines still do very well and provide a huge boost.. not worth waiting

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Adrian H

@Adrian_H

11 months

This is even crazier than I would have imagined $SAVA

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Adrian H

@Adrian_H

2 years

So, where is the prolific editor at 71.41.248.226 doing her editing from? ..direct from the Cassava Sciences offices. So now you know how the $SAVA VP of Neuroscience spends her days.

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Adrian H

@Adrian_H

4 years

@jeremyfaust The REGN abs have very good rationale, no safety issues so far, and in some cases (ie. if he's not mounting a good response himself) could help a lot. Too late to use as prophylaxis, but little harm in trying. It's in poor taste for him to get special treatment, but so it goes

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Adrian H

@Adrian_H

9 months

Guys, instead of only doing this jihad only against plagiarism by a bunch of mostly irrelevant social science elites, could we also go after scientific misconduct and pseudo-research that actually costs the government (and investors) millions?

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Adrian H

@Adrian_H

1 year

As veteran short sellers like to say, it’s always a good sign when a CFO leaves $ENVX

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Adrian H

@Adrian_H

4 years

@meganranney @DataDrivenMD There are starting to be way too many people inside bars like it’s 2019.. can’t we all just wait another couple of months so that we can enjoy the summer?

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Adrian H

@Adrian_H

3 years

@michaelmina_lab delta does not really evade the antibodies to the original vaccines

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Adrian H

@Adrian_H

2 years

BOOM! This paper was Wang's original sin underlying ALL of the $SAVA nonsense -- the claim that Naloxone binds to Filamin-A. It is bogus, and now retracted. IT IS ALL MADE UP. THEIR DRUG DOES NOT BIND A TARGET AND COULD NOT HAVE BEEN DISCOVERED AS DESCRIBED IN THEIR PATENTS.

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Adrian H

@Adrian_H

2 years

Check out our poster at #CTAD22 presenting our analysis of the science behind Simufilam, and our attempts to experimentally test the binding of Naloxone and Simufilam to their purported pentapeptide target. $SAVA

CTADposter_LP105A_RigorReplication_Simufilam_SF2022.pdf

Shared with Dropbox

www.dropbox.com

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Adrian H

@Adrian_H

4 years

@WomenInStat @daniela_witten I have a joke about problems with comparing complicated distributions using just a summary statistic, but it’s a little too mean.

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Adrian H

@Adrian_H

4 years

Imagine if 60 Minutes actually used their still-formidable platform to ask hard-hitting questions and speak truth to power, rather than doing photo ops with audio and impotent philosophizing.

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Adrian H

@Adrian_H

2 years

There are actually FIVE @PLOSONE retractions of papers from Dr. HY Wang today $SAVA

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Adrian H

@Adrian_H

3 years

Cassava Sciences has two products in development: Simufilam, & SavaDx, a proprietary diagnostic for Alzheimer’s. According to $SAVA 10K, SavaDx is NOT protected by patents, so actual molecules measured by SavaDx have been a key, closely guarded trade secret. Until today.. 🧵

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Adrian H

@Adrian_H

5 months

@WagieCapital @FUDdaily I don’t think a war is the right path but a weed shop on every block is not a good idea either

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Adrian H

@Adrian_H

2 years

Another editorial retraction for Dr.Hoau-Yan Wang, from a collaboration with Servier. (and even @brunovellas agrees!) It is all made up. $SAVA @MicrobiomDigest

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Adrian H

@Adrian_H

2 years

My statement today at the @CUNY Manhattan Borough Public Hearing IT IS ALL MADE UP. Enough is enough, @ChancellorCUNY @CUNYResearch @Vgbcc1 and Mr. Davis $SAVA

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Adrian H

@Adrian_H

2 years

@emilynussbaum

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Adrian H

@Adrian_H

2 months

Exclusive footage of Remi’s final $SAVA board meeting… (It’s parody, guys.. for my view of the real story do check out )

Remi's Final Board Meeting at Cassava $SAVA

Exclusive Video of Remi's Final Cassava Sciences Board Meeting and Parting Advice to Rick (parody)

www.captiongenerator.com

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Adrian H

@Adrian_H

3 years

$ARKK is just a bucket of high growth names, and they've actually made some interesting and good picks. Yeah $TSLA is sketch but it's done very well. Beta gonna beta, it might well go down, but there's no conspiracy and no systemic issue and get over it already.

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Adrian H

@Adrian_H

3 months

would a reasonable reader agree that a fair summary of the allegations in this indictment is that "IT'S ALL MADE UP"? $SAVA

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Adrian H

@Adrian_H

4 years

@EpiEllie @StevenSalzberg1 Especially since the vaccines that will be available first are using new technologies where it is harder to predict or rule out potential risks.

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Adrian H

@Adrian_H

2 years

the bankrupt retailer / bankrupt movie theater / Alzheimer's scam factor really outperforming today in anticipation of a strong CPI reading

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Adrian H

@Adrian_H

3 years

Here's a little tip for biotech frauds trying to obscure information about what proteins you actually measure to make your wacky, miraculously accurate Alzheimer's diagnostic more inscrutable: the labels are still there in the PDF even if you make the text white. $SAVA

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Adrian H

@Adrian_H

6 years

@Superninfreak @Susan_Hennessey He was disrespectful to the Institution, which is bigger than all of them, and by extension to the entire Nation.

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Adrian H

@Adrian_H

3 years

And so it begins.. $SAVA Thank you for finally doing the right thing, @MarinaP63

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Adrian H

@Adrian_H

3 months

guys, it now only is a matter of when, not if.. $SAVA

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Adrian H

@Adrian_H

2 months

How could anyone have predicted this? $SAVA

Adrian H

@Adrian_H

3 months

keeping Remi in charge at $SAVA is going to be untenable for the board, IMO

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Adrian H

@Adrian_H

3 years

Burns : Remi :: Holmes : Sunny ? the psychology of these people is fascinating $SAVA

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Adrian H

@Adrian_H

2 years

I’m getting really sick of seeing retweets of that toothy CFA clickbait grifter

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Adrian H

@Adrian_H

2 years

At least I'm keeping up my streak of getting into Nature once every decade or two $SAVA

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Adrian H

@Adrian_H

3 years

Looks like I also got a little present from the NIH FOIA office today! 750 pages of potentially fraudulent grant applications.. $SAVA

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Adrian H

@Adrian_H

3 years

Decent chance that $SAVA ends red.. Just another pathetic and increasingly desperate pump-and-dump onto the ignorant and credulous. It is all made up.

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Adrian H

@Adrian_H

1 year

instead of a debate, how about we just have a fight between RFK and a measles virus

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Adrian H

@Adrian_H

16 days

This may be one of the most idiotic legal “scholarship” ever written.. bizarre criticism of short sellers based on.. $NWBO Hard to believe this is organic or anyone really this stupid.. outdoes even Mitts @MidwestHedgie @adamfeuerstein @muddywatersre

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Adrian H

@Adrian_H

3 years

What would happen if 10% of the time and attention journalists are spending gawking at Holmes’ trial were spent reporting and exposing ongoing scams like $CYDY, $CVM, $OCGN and $SAVA?

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Adrian H

@Adrian_H

2 months

They should have set a condition that he is not allowed to use Photoshop any more $SAVA

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Adrian H

@Adrian_H

3 years

Another BEAUTIFUL analysis by Gonaxis quadrilateralis on Pubpeer to quantify the painfully obvious image duplication in Wang 2017, first noted by @MicrobiomDigest and @PSBROOKES . Sometimes a picture is worth a thousand words. $SAVA cc: @KarlHerrup

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Adrian H

@Adrian_H

3 years

🚨🔬🧠 SHAPE ROTATOR TEST FOR SCIENTISTS! 🧠🔬🚨 If you are a neuroscientist, or anyone who cares about reality, and you can see the rotated / duplicated image here, please retweet & check out this @MicrobiomDigest thread $SAVA

Elisabeth Bik

@MicrobiomDigest

3 years

Me: These two panels appear to be duplicated. Editor: Software did not flag this as a duplication. Those "subjective impressions" alone are not sufficient to support a claim of image duplication. 😢

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Adrian H

@Adrian_H

3 years

my $SAVA tweeting might be a little light today.. I’m in the lab running some initial assay VALIDATION experiments.. because that’s how we roll

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Adrian H

@Adrian_H

6 months

Cassava achieves the rare distinction of earning an “Editorial Note” on the Ph2b *preprint* that they never could get published.. $SAVA @cpiller @adamfeuerstein @apoorva_nyc @joewalkerWSJ @MicrobiomDigest @RetractionWatch

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Adrian H

@Adrian_H

3 years

Here’s my letter to @JuanLerma1 concerning the latest round of apparent data fabrication and cover-up by $SAVA & Dr. Wang, in Neuroscience The cowardice and complicity of journals & their editors in cover-ups needs to end. @MicrobiomDigest @MarinaP63

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Adrian H

@Adrian_H

2 months

How it started vs. how it’s going, “science” edition.. 🤔 $SAVA

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Adrian H

@Adrian_H

2 years

@grahamwalker @drsiyabmd Why worry about fecal contamination of drinking water? Drinking bugs ought to just toughen up your immune system.

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Adrian H

@Adrian_H

2 years

1. Remi must be feeling pretty scared to send this out about $SAVA. Not his usual style. 2. @realjacobbraun who put out a SA story with a deliberately misleading headline yesterday to successfully pump the stock may be in some hot water. I hear @jbeidel is good.

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Adrian H

@Adrian_H

1 year

@StockJabber @AlderLaneEggs As a former short-seller, how can he believe that it is acceptable to dox, insult, and disparage anyone who disagrees with him about a stock, including former employees? And why does he think it is OK to exaggerate and lie about public companies in which he holds positions?

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Adrian H

@Adrian_H

4 months

@ItaiYanai but you never heard about the other eight postdocs whose experiments didn't lead to a big discovery

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Adrian H

@Adrian_H

5 months

How it started…. How it’s going $ENVX #journeytoZero

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Adrian H

@Adrian_H

2 years

The $SAVA fans are some lovely people

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Adrian H

@Adrian_H

2 years

Downtown San Francisco after 8pm doesn’t quite feel dangerous (like Baltimore dangerous) but it sure does feel like you are inside a post-apocalyptic video game

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Adrian H

@Adrian_H

3 years

I wonder how much money was transferred from twitter users to Jeff Ubben thanks to the Cohodes, Reyes and Balog $APPH cheerleading squad

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Adrian H

@Adrian_H

3 years

Within the last few days, Cassava Sciences $SAVA have deleted their Scientific Advisory Board link from their homepage... (the page is still there if you have the URL: ) Are you still working there, @BJSahakian ? How about you, Dr. Arnold? @joewalkerWSJ

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Adrian H

@Adrian_H

2 years

Does anyone else's plotting software have this problem where the bars aren't all aligned with the X-axis and the error bars are all drawn a little different? Any ideas what might cause this? Weird, eh? @MicrobiomDigest @RetractionWatch @emmcnally

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Adrian H

@Adrian_H

2 years

The $SAVA story is just getting started. All the enablers, all the adults who haven’t been doing their jobs, all those assisting in the attempted cover-ups need to come clean..

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Adrian H

@Adrian_H

2 years

A few subtleties got mangled, but I managed to call out Simufilam as "an imaginary drug that does nothing" in the Daily Mail $SAVA

'Fraudulent' Alzheimer's study gave false hope to families

It's alleged a pivotal study on the cause of Alzheimer's disease contained manipulated results, potentially leading other scientists down a blind alley.

www.dailymail.co.uk

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Adrian H

@Adrian_H

4 years

@Caroline_Bartma It's next door to the pub for chemists called Stir Bar

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Adrian H

@Adrian_H

4 years

@BeschlossDC it's just as well, because they might have been super-spreaders otherwise

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Adrian H

@Adrian_H

1 month

ya think? $SAVA

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Adrian H

@Adrian_H

3 years

Some great new analysis on PubPeer pointing out and quantifying the latest $SAVA lies and fabrications that were already plain to see for anyone who just looked.

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Adrian H

@Adrian_H

11 months

The $SAVA Discord is falling into disarray.. people are starting to violate the Prime Directive, which is to NEVER post Adrian tweets

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Adrian H

@Adrian_H

1 year

who wants to start a superconducting battery company I know some guys who can help with the promote

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Adrian H

@Adrian_H

6 years

I don't think I've ever before been looking forward so much to Monday morning on a Friday night. $MDXG

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Adrian H

@Adrian_H

5 years

@apoorva_nyc It's very interesting and compelling, but I don't think anything is "very clear" until someone is able to do surveillance and testing on some real random samples

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Adrian H

@Adrian_H

2 years

@RoamResearch could you maybe stop with the secret features, and provide some reasonable documentation and explanation to paying customers?

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Adrian H

@Adrian_H

1 year

@ResearchGrizzly Better not be Hershey’s

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Adrian H

@Adrian_H

6 months

There are many crazy things in the FDA 483 report from their inspection of CUNY and Dr. Wang, but this tops them all.. Wang no longer has Photoshop because the Department of Justice seized his computer. $SAVA

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Adrian H

@Adrian_H

9 months

This is a good lesson in why it is critically important to cite your sources and show your data. $SAVA

Report and Recommendations – #105 in Cassava Sciences, Inc. v. Bredt (S.D.N.Y., 1:22-cv-09409) –...

REPORT & RECOMMENDATION TO THE HONORABLE GREGORY H. WOODS re: 86 MOTION to Dismiss the First Amended Complaint. filed by Enea Milioris, Adrian Heilbut, Jesse Brodkin. For the reasons above, I...

www.courtlistener.com

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Adrian H

@Adrian_H

3 months

If only there had been signs or some kind of warnings for shareholders.. $SAVA

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Adrian H

@Adrian_H

1 year

$SAVA motion to dismiss the Tx securities lawsuit against them was DENIED (They let Friedmann off the hook to sort it out with God.) This is not good news for $SAVA

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Adrian H

@Adrian_H

1 year

has there been a case like this of an attempt at a class action securities lawsuit by *investors* against a short seller before? This is nuts. $AI

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Adrian H

@Adrian_H

1 year

No rest until I collect enough of these to wallpaper the entire bathroom

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Adrian H

@Adrian_H

3 years

It is a really, really bad idea to think you can fool @MicrobiomDigest

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Adrian H

@Adrian_H

11 months

so this is definitely a bit weird.. $SAVA How it started... How it's going...

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Adrian H

@Adrian_H

6 years

the insanity of $MDXG has brought good people together from afar like nothing I have seen. A true sisterhood/brotherhood who wouldn't otherwise be able to agree on a pizza order: new yorkers, californians, chicagoans, texans, Christians, Jews, MAGA, gun fans, & even Canadians

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Adrian H

@Adrian_H

3 years

I disagree with @AlderLaneeggs about a quite a lot of things, but I did learn at least one good trick from him, which is that I DON'T LET GO OF THE ROPE and I DON'T STOP $SAVA

Adrian H

@Adrian_H

3 years

In Wang, 2012 (J Neurosci), Dr. Wang reports using two α7 nAChR antibodies in the Methods: SC-5544, & SC-65844. This is another impressive feat by Wang, because SC-65844 is an antibody to **α1** nAChR $SAVA @MarinaP63 @MicrobiomDigest #ScienceIntegrity

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Adrian H

@Adrian_H

2 years

When you are running a fraud, one of the most important things is to have a strong astroturfing game. You need to make sure that your narrative is the dominant one, and you must try to discredit your detractors whenever possible. $SAVA

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Adrian H

@Adrian_H

3 months

UH OH $SAVA

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Adrian H

@Adrian_H

1 year

So who wants me to join in on this $ENVX spaces and help clarify some facts?

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Adrian H

@Adrian_H

4 years

@jeremyfaust

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Adrian H

@Adrian_H

3 years

Pity there were no warning signs here... $SAVA

Joseph Walker

@joewalkerWSJ

3 years

The Securities and Exchange Commission is investigating Cassava Sciences, people familiar with the matter say. The company’s experimental Alzheimer’s drug has enthralled investors and raised questions about the research backing it up. via @WSJ

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Adrian H

@Adrian_H

1 year

So Dr. Chuck Spruck, the western blot "expert" that $SAVA likes to rely on for support and astroturfing, really does seem to have experience with western blot duplication himself.. it's the clown show that never ends @MicrobiomDigest @ClicksAndHisses

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Adrian H

@Adrian_H

1 year

Once you realize Marc is just rehashing the same tired scripts over and over in his completely vacuous 24/7 WWF pro wrestler act you might as well just laugh at him and enjoy the entertainment $NKLA $APPH $ENVX $OSTK

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Adrian H

@Adrian_H

10 months

I can think of only two reasons to put a senior ex-FBI official on your board of directors while under DOJ investigation, and neither of them are very confidence-inspiring.

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Adrian H

@Adrian_H

2 years

it's weird how $SAVA has suddenly become SO insistent that all the biomarkers they ever ran or are running were "research use only" "non-safety related" and "exploratory" -- despite being used to screen & qualify patients for inclusion in clinical trials (& used as 1e endpoints)

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Adrian H

@Adrian_H

1 year

YBS disclosed its side of manufacturing agreement with $ENVX They DO NOT disclose actually having secured $70m loan they need This makes $ENVX press release claims of having secured $70m in financing inaccurate, IMO, because YBS doesn’t yet have it

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Adrian H

@Adrian_H

3 years

I'm shocked, shocked! $SAVA

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Adrian H

@Adrian_H

10 months

Collaborating with $SAVA may lead to unexpected side effects.. attract the attention of @MicrobiomDigest at your peril..

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Adrian H

@Adrian_H

3 years

This is curious.. just a few weeks ago, Dr. Hoau-Yan Wang was scheduled to teach a grad Neuropharmacology course at CUNY City College. Now, the listing has disappeared & there's no Spring 22 neuropharmacology $SAVA @CUNYNeuro I wonder what happened?